Snapshot A 36-year-old woman presents to her physician's clinic with pain and swelling in the hands and wrists. She reports morning stiffness that lasts for approximately 1 hour which later improves. She also states to be experiencing symptoms of depression and fatigue. On physican exam, there is decreased grip strength and 4/5 strength on wrist extension. There is tenderness to palpation and swelling of the proximal interphalangeal joints and metacarpophalangeal joints. Introduction Definition login to view 1 more bullet Epidemiology login to view 7 more bullets Etiology login to view 1 more bullet Pathogenesis login to view 5 more bullets Genetics login to view 1 more bullet Associated conditions login to view 6 more bullets Prognosis login to view 1 more bullet Presentation Symptoms login to view 6 more bullets Physical exam login to view 9 more bullets Imaging Radiography login to view 10 more bullets Studies Labs login to view 9 more bullets Diagnostic criteria login to view 1 more bullet Differential Systemic lupus erythematous Psoriatic arthritis Scleroderma Polymyalgia rheumatica Gout Treatment Conservative login to view 3 more bullets Pharmacologic login to view 15 more bullets Operative login to view 3 more bullets Complications Hand deformities Atlantoaxial subluxation Popliteal cyst