Snapshot A 7-year-old girl is brought to the emergency department after experiencing a risk fracture. The patient fell down to the ground and has not hit her head. This has never happened before. The patient's parents reports their child states she has pain in bones and at times feels weak. On physical exam, there is tenderness to palpation of the wrist with a waddling gait. Laboratory testing is notable for a decreased serum calcium and phosphate level, and increased alkaline phosphatase and parathyroid hormone. (Rickets secondary to vitamin D defiency) Introduction Clinical definition login to view 4 more bullets Epidemiology login to view 12 more bullets Etiology login to view 12 more bullets Pathogenesis login to view 1 more bullet Prognosis login to view 1 more bullet Presentation Symptoms login to view 4 more bullets Physical exam login to view 10 more bullets Imaging Radiography login to view 8 more bullets Studies Labs login to view 2 more bullets Laboratory Abnormalities in Select Bone Disorders Etiology Serum Phosphate Serum Calcium Serum Alkaline Phosphatase Parathyroid Hormone Osteomalacia/rickets Decreased Decreased Increased Increased Osteoporosis Normal Normal Normal Normal Osteopetrosis Normal Normal or decreased Normal Normal Paget disease of the bone Normal Normal Elevated Normal Osteitis fibrosa cystica Primaryhyperparathyroidism decreased Secondaryhyperparathyroidism increased Primaryhyperparathyroidism increased Secondaryhyperparathyroidism decreased Primary and secondary hyperparathyroidism increased Primary and secondary hyperparathyroidism increased Hypervitaminosis D Increased Increased Normal Decreased Differential Child abuse Osteogenesis imperfecta Osteoporosis Paget disease of bone Multiple myeloma Treatment Medical login to view 6 more bullets Complications Fractures Growth abnormalities