Snapshot A 26-year-old woman presents to the dermatology clinic for fatigue, weakness, and fevers for the past month. She reports significant weight loss despite eating a normal diet. She reports that she sunburns very easily and has a facial rash that is hard to cover with makeup. On physical exam, she has a butterfly rash with nasolabial sparing on her face, several discoid lesions on her fingers, and a erythematous rash on her chest in a V-neck distribution. On laboratory exam, she has a highly positive antinuclear antibody and positive anti-double-stranded DNA antibody. Introduction Clinical definition login to view 2 more bullets Epidemiology login to view 8 more bullets Pathogenesis login to view 9 more bullets Associated conditions login to view 14 more bullets Prognosis login to view 1 more bullet Presentation Symptoms login to view 5 more bullets Physical exam login to view 18 more bullets Studies Labs login to view 21 more bullets Urinalysis login to view 1 more bullet Making the diagnosis login to view 14 more bullets Differential Acne rosacea login to view 3 more bullets Sarcoidosis login to view 4 more bullets Treatment Management approach login to view 2 more bullets Conservative login to view 3 more bullets Medical login to view 34 more bullets Complications Causes of death in SLE login to view 3 more bullets Lupus nephropathy login to view 1 more bullet Cardiovascular disease login to view 2 more bullets Thrombosis