Snapshot A 32-year-old women presents to her physician complaining of double vision. This has been very distressing for her. She has a past medical history significant for type 1 diabetes, treated with a continuous subcutaneous insulin pump. Upon further questioning, she mentions she experienced arm weakness and numbness that resolved spontaneously over the course of a couple weeks. Physical examination is notable for impaired adduction of the right eye, and nystagmus on abduction of the left eye on left lateral gaze. Introduction Autoimmune inflammation/demyelination of CNS neurons login to view 4 more bullets Epidemiology login to view 7 more bullets Presentation Symptoms - may have multiple neurologic symptoms separated in time and space login to view 15 more bullets Evaluation LP login to view 5 more bullets Imaging login to view 5 more bullets Differential Acute disseminated encephalomyelitis Neuromyelitis optica (NMO) Idiopathic transverse myelitis Treatment Medical login to view 8 more bullets Symptomatic treatment for neurogenic bladder, spasticity, and pain Prognosis, Prevention, and Complications Can exhibit multiple patterns of disability progression login to view 3 more bullets