Snapshot A 67-year-old male presents with poor attention and getting lost while driving. He is accompanied by his wife. She reports that he would have episodes of staring into space and disorganized speech. His wife also reports that he would have full conversations with himself in the living room. She says that he was talking to his brother, who is deceased. Postural instability and bradykinesia is noted on physical exam. Introduction Degenerative dementia associated with login to view 6 more bullets Poor response to dopamine agonist therapy Lewy body login to view 2 more bullets Epidemiology login to view 2 more bullets Presentation Symptoms login to view 9 more bullets Evaluation Clinical diagnosis Histology login to view 4 more bullets Differential Alzheimer disease Parkinson disease Vascular dementia Creutzfeldt-Jakob disease Treatment Cholinesterase inhibitors login to view 3 more bullets Prognosis, Prevention, Complications Prognosis login to view 1 more bullet