Snapshot A 27-year-old male presents with an unprovoked convulsive episode. Medical history is noncontributory. Family history is significant for clear cell renal cell carcinoma in his father, resulting in death. The exact cause of his paternal grandfather’s death is unclear, but is thought to be due to a “bleed in the brain.” Head CT is performed. Introduction Autosomal dominant syndrome secondary to VHL gene mutation on chromosome 3 login to view 6 more bullets Presentation Associated with: login to view 6 more bullets Evaluation Genetic testing login to view 1 more bullet Imaging techniques used to identify associated diseases login to view 1 more bullet Differential Multiple endocrine neoplasia, type 2 (MEN 2) Pheochromocytoma Autosomal dominant polycystic kidney disease Treatment Medical management login to view 2 more bullets Surgical management login to view 1 more bullet Prognosis, Prevention, and Complications Complications login to view 1 more bullet