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Updated: Jun 10 2021

Adrenal Cortex and Medulla

  • Overview
      • Adrenal Cortex and Medulla
      • Primary Regulatory Control
      • Secretory products
      • Renin-angiotensin
      • Aldosterone
      • ACTH, hypothalamic CRH
      • Zona fasciculata
      • Cortisol and sex hormones
      • ACTH, hypothalamic CRH
      • Zona reticularis
      • Sex hormones (e.g. androgens)
      • Preganglionic sympathetic fibers
      • Medulla
      • Catecholamines (Epi, NE)
    • Glomerulosa (salt), fasciculata (sugar), reticularis (sex)
      • "The deeper you go, the sweeter it gets."
  • Adrenal Circulation
    • Both the left and right adrenals receive arterial blood supply in the same fashion
      • paired superior suprarenal arteries - derived from inferior phrenic arteries
      • paired middle suprarenal arteries - derived directly from abdominal aorta
      • paired inferior suprarenal arteris - derived from the adjacent renal arteries
    • The left and right adrenals have differing venous drainage
      • left adrenal venous drainage is through the left adrenal vein to the left renal vein and finally to the IVC
      • right adrenal venous drainage is through the right adrenal vein to the IVC
    • Recall the same pattern for the left and right gonadal artery/vein
  • Selected Pathology
    • Pheochromocytoma
    • Neuroblastoma
    • Conn's syndrome
    • Cushing's syndrome
    • Addison's disease
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