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Updated: Sep 7 2018

Polyglandular Deficiency Syndrome

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https://upload.medbullets.com/topic/111085/images/mucocutaneous candidasis.jpg
  • Introduction
    • Syndromes with associated pathologies involving
      • Addison's disease + para/thyroid disease + GI disease
    • There are 2 types
      • Type I
        • AR inheritance with onset in childhood
        • No HLA relationship
        • Associated conditions
          • Addison's disease
          • primary hypoparathyroidism
          • mucocutaneous candidiasis
      • Type II
        • AD inheritance with onset in young adulthood
        • HLA-Dr3 and Dr4 association
        • Associated conditions
          • Addison's disease
          • Hashimoto's thyroiditis
          • Type I DM
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