Introduction Glucose less than about 50 mg/dL Caused by over-administration of insulin in type I diabetes exercise in type I diabetes less commonly induced by insulin secretagogues (e.g. sulfonylureas) Presentation Symptoms adrenergic symptoms sweating anxiety palpitation mydriasis numbness tingling arise 1-5 hours post-prandially Treatment Medical carbohydrate intake (fruit juice) glucagon IM injection if unconscious side effects include vomiting Prognosis, Prevention, and Complications Diabetic patients on β-blockers are at risk for severe hypoglycemia because early adrenergic symptoms do not present sweating may be only sign (sweat glands are innervated by a cholinergic synapse despite sympathetic neuron)