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Updated: Sep 17 2021

Hypothyroidism vs Hyperthyroidism

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  • Presentation
      • Symptoms/Physical Exam
      • Hypothyroidism
      • Hyperthyroidism
      • Cold intolerance (↓ heat production)
      • Heat intolerance (↑ heat production)
      • Weight gain
      • ↓ appetite
      • Weight loss
      • ↑ appetite
      • Hypoactivity
      • lLethargy
      • Fatigue
      • Weakness
      • Hyperactivity
      • Constipation
      • Diarrhea
      • ↓ reflexes
      • ↑ reflexes
      • Bradycardia
      • Tachycardia, palpitations, arrhythmias
      • Dry, cool skin
      • Coarse, brittle hair
      • Warm, moist skin
      • Fine hair
      • Diastolic hypertension (Na/H2O retention)
      • Systolic hypertension
      • Myxedema (facial/periorbital)
      • Osteoporosis
    • Heat intolerance (↑ heat production)
    • Weight loss
    • ↑ appetite
    • Hyperactivity
    • Diarrhea
    • ↑ reflexes
    • Tachycardia, palpitations, arrhythmias
    • Warm, moist skin
    • Fine hair
  • Evaluation
      • Labs
      • Hypothyroidism
      • Hyperthyroidism
      • ↓ TSH (best first test)
      • ↓ total T4
      • ↑ total T4
      • ↓ free T4
      • ↑ free T4
      • Hyper cholesterolemia (↓ LDL receptor synthesis)
      • Hypo cholesterolemia (↑ LDL receptor synthesis)
      • Elevated serum creatine kinase
      • --
    • ↓ TSH (best first test)
    • ↑ total T4
    • ↑ free T4
  • Treatment
      • Treatment
      • Hypothyroidism
      • Hyperthyroidism
      • Levothyroxine
      • ThionamidesAblative131I therapy
      • Ablative 131I therapy
    • Thionamides
    • Ablative 131I therapy
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