Overview P450 P450 Inducers P450 Inhibitors St. John's Wort Phenytoin Barbiturates Rifampin Griseofulvin Carbamazepine Efavirenz Modafinil Cyclophosphamide Broccoli, brussel sprouts, and char-grilled meats Ethanol Tricyclic antidepressants Fluoroquinolones Keto- and itraconazole Amiodarone Quinidine PPI's Cimetidine Diltiazem Verapamil Isoniazid SSRI's Grapefruit juice Protease inhibitors (PIs) NNRTIs Ritonavir Valproic acid Sulfa Drug Reactions Patients who have sulfa (sulfonamide) allergies will have a wide range of allergies to the following sulfa drugs Sulfa Drug Reactions Sulfa Drugs Reactions Trimethoprim (TMP) Sulfamethoxazole (SMX) Sulfasalazine Sulfonylureas (tolbutamide, glipizide) Sumatriptan Celecoxib Furosemide Thiazides (hydrochlorothiazide) Probenecid Fosamprenavir Acetazolamide Mafenide Agranulocytosis Fever Fulminant hepatic necrosis Hemolytic anemia Pruritic rash Stevens-Johnson syndrome Thrombocytopenia Toxic epidermal necrolysis Urticaria