Updated: 12/15/2020

Drug Interactions

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P450 Inducers
P450 Inhibitors
  • St. John's Wort
  • Phenytoin
  • Barbiturates
  • Rifampin
  • Griseofulvin
  • Carbamazepine 
  • Efavirenz
  • Modafinil
  • Cyclophosphamide
  • Broccoli, brussel sprouts, and char-grilled meats
  • Ethanol
  • Tricyclic antidepressants
  • Fluoroquinolones
  • Keto- and itraconazole
  • Amiodarone
  • Quinidine
  • PPI's
  • Cimetidine
  • Diltiazem
  • Verapamil
  • Isoniazid
  • SSRI's 
  • Grapefruit juice 
  • Protease inhibitors (PIs)
  • NNRTIs
  • Ritonavir
  • Valproic acid

 

Sulfa Drug Reactions
  • Patients who have sulfa (sulfonamide) allergies will have a wide range of allergies to the following sulfa drugs
Sulfa Drugs
Reactions
  • Trimethoprim (TMP)
  • Sulfamethoxazole (SMX)
  • Sulfasalazine
  • Sulfonylureas (tolbutamide, glipizide)
  • Sumatriptan
  • Celecoxib
  • Furosemide
  • Thiazides (hydrochlorothiazide)
  • Probenecid
  • Fosamprenavir
  • Acetazolamide
  • Mafenide
  • Agranulocytosis
  • Fever
  • Fulminant hepatic necrosis
  • Hemolytic anemia
  • Pruritic rash
  • Stevens-Johnson syndrome
  • Thrombocytopenia
  • Toxic epidermal necrolysis
  • Urticaria

References

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