Therapeutic Actions for Muscarinic Antagonists Therapeutic Actions for Muscarinic Antagonists Drug Organ System Application and Comments Atropine, homatropine, tropicamide Eye and Cardiac Causes mydriasis and cycloplegia Used for ophthalmologic exams Can be used for post-MI bradyarrythmias Benztropine CNS Parkinson's disease Scopolamine CNS Motion sickness Fast onset Ipratropium Respiratory Asthma COPD Tiotropium produces a longer bronchodilator effect Relief of rhinorrhea with common cold, allergic and nonallergic rhinitis Oxybutynin, trospium, glycopyrrolate Genitourinary Reduce urgency in mild cystitis Reduce bladder spasms after urologic surgery Methscopolamine, pirenzepine, propantheline Gastrointestinal Peptic ulcer treatment Atropine Muscarinic antagonist login to view 1 more bullet Organ system login to view 3 more bullets Toxicity login to view 5 more bullets Atropine adage: "hot as a hare, dry as a bone, red as a beet, blind as a bat, mad as a hatter, the bowel and bladder loser their tone, and the heart runs alone"