Review Question - QID 109901

A 12-year-old girl is brought to the pediatrician by her father who is concerned about the child’s ability to sit in a moving vehicle. She frequently develops nausea and dizziness when riding in a car for more than 10 minutes. The child has vomited twice over the past month while riding in the car. Her symptoms are significantly impairing her ability to make it to school on time without having to stop and get out of the car. The child does well in school and has several close friends. On examination, the child is well-appearing and appropriately interactive. Dix-Hallpike maneuver is negative. Her gait is normal. Strength and range of motion are full and symmetric bilaterally in the upper and lower extremities. The father would like to know if there is anything his daughter can take to be able to sit in a moving vehicle without feeling ill. A medication with which of the following mechanisms of action is indicated to manage this patient’s symptoms?