Somatropin Growth hormone (GH) mimetic Mechanism agonist at GH receptors increases production of insulin growth factor-1 (IGF-1) Clinical use GH deficiency increase adult height for children with conditions associated with short stature Turner syndrome wasting in HIV infection short bowel syndrome Toxicity scoliosis edema gynecomastia increased CYP450 activity Octreotide Somatostatin mimetic Mechanism agonist at somatostatin receptors Clinical use acromegaly carcinoid gastrinoma glucagonoma acute esophageal variceal bleed Toxicity GI upset gallstones bradycardia Oxytocin Mechanism agonist at oxytocin receptor Clinical use stimulation of labor uterine contractions control of uterine hemorrhage after delivery stimulate milk letdown Toxicity fetal distress abruptio placentae uterine rupture Desmopressin ADH (vasopressin) mimetic Mechanism agonist at vasopressin V2 receptors Clinical use central (pituitary) diabetes insipidus hemophilia A (factor VIII deficiency) increases availability of factor VIII von Willebrand disease increases release of von Willebrand factor from endothelial cells Toxicity GI upset headache hyponatremia allergic reaction
QUESTIONS 1 of 1 1 Previous Next (M1.EC.17.4799) A 33-year-old G1P0 at 39 weeks gestation is admitted to the labor and delivery floor for induction of labor. She feels well and is no acute distress. She is accompanied by her husband. Her past medical history is notable for major depressive disorder and generalized anxiety disorder. She takes sertraline. Her temperature is 99.2°F (37.3°C), blood pressure is 120/75 mmHg, pulse is 95/min, and respirations are 18/min. To initiate labor induction, the obstetrician injects the patient with a hormone that is endogenously made in the hypothalamus and released by the posterior pituitary. This medication is associated with an increased risk of which of the following complications? QID: 109331 Type & Select Correct Answer 1 Placental abruption 66% (95/145) 2 Vasa previa 7% (10/145) 3 Placenta accreta 9% (13/145) 4 Preeclampsia 13% (19/145) 5 Oligohydramnios 3% (4/145) M 4 Question Complexity C Question Importance Select Answer to see Preferred Response SUBMIT RESPONSE 1 Review Tested Concept Review Full Topic