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Review Question - QID 109331

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QID 109331 (Type "109331" in App Search)
A 33-year-old G1P0 at 39 weeks gestation is admitted to the labor and delivery floor for induction of labor. She feels well and is no acute distress. She is accompanied by her husband. Her past medical history is notable for major depressive disorder and generalized anxiety disorder. She takes sertraline. Her temperature is 99.2°F (37.3°C), blood pressure is 120/75 mmHg, pulse is 95/min, and respirations are 18/min. To initiate labor induction, the obstetrician injects the patient with a hormone that is endogenously made in the hypothalamus and released by the posterior pituitary. This medication is associated with an increased risk of which of the following complications?

Placental abruption

63%

149/236

Vasa previa

6%

13/236

Placenta accreta

8%

18/236

Preeclampsia

17%

39/236

Oligohydramnios

3%

6/236

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The patient in this vignette will receive oxytocin to induce uterine contractions. Oxytocin is associated with an increased risk of placental abruption and uterine rupture.

Oxytocin is a hormone that is produced in the hypothalamic paraventricular nucleus but stored and released by the posterior pituitary. The downstream effects of oxytocin include induction of uterine contractions and stimulation of milk letdown. It is commonly used to induce labor and control postpartum uterine bleeding.

Incorrect Answers:
Answer 2: Vasa previa is a pregnancy complication characterized by fetal blood vessels crossing or running adjacent to the uterine opening. It develops early in pregnancy and is not associated with oxytocin use.

Answer 3: Placenta accreta is a pregnancy complication characterized by placental invasion into or past the myometrium. This can lead to heavy postpartum bleeding and an inability to deliver the placenta. It is not associated with oxytocin use.

Answer 4: Preeclampsia is a disorder arising during pregnancy that is characterized by hypertension, proteinuria, and organ dysfunction. It is not associated with oxytocin use.

Answer 5: Oligohydramnios is a pregnancy complication characterized by decreased amniotic fluid. It is not associated with oxytocin use.

Bullet Summary:
Oxytocin promotes uterine contractions in childbirth and is associated with an increased risk of placental abruption and uterine rupture.

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