Introduction Syndrome characterized by insulin resistance with hyperinsulinemia and obesity Associated conditions polycystic ovarian syndrome Presentation Physical exam acanthosis nigricans sign of hyperinsulinemia hypertension (>130/85 mmHg) obesity as evaluated by waist circumference Evaluation Serology hypertriglyceridemia (>150 mg/dL) hyperglycemia (>110 mg/dL fasting) decreased HDL cholesterol (<40 mg/dL in men, <50 mg/dL in women) BMI = weight in kg / (height in meters)2 Treatment Medical with lifestyle changes weight loss will increase insulin sensitivity decrease blood pressure increase ghrelin level decrease leptin level diabetic medications (metformin) antihypertensive agents (ACE-inhibitors or thiazides) cholesterol-loweing agents (statins) Prognosis, Prevention, and Complications ↑ risk of Alzheimers, coronary artery disease
QUESTIONS 1 of 3 1 2 3 Previous Next Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK (M1.EC.15.75) A 50-year-old female with a past medical history of hypertension comes to your clinic for a refill of her lisinopril medication. She is also taking lovastatin and hydrochlorothiazide. The patient's vital signs are as follows: HR 80, BP 150/100, and BMI 40. Physical exam is remarkable for a waist-to-hip ratio of 1.0 and the presence of diffuse dark patches on her skin (Figure A). Her fasting lab results are as follows: Sodium: 145 mmol/L, Potassium: 5.0 mmol/L, Chloride: 105 mmol/L, Bicarbonate: 25 mmol/L, BUN: 10 mg/dL, Creatinine: 1.0 mg/dL, Glucose: 200 mg/dL, Triglyceride: 200 mg/dL, LDL: 250 mg/dL, Total cholesterol: 300 mg/dL, HDL: 30 mg/dL, and Hemoglobin A1C: 7.0%. The patient's history, physical exam, and laboratory findings are most consistent with which of the following? QID: 106830 FIGURES: A Type & Select Correct Answer 1 Hypothyroidism 4% (4/108) 2 Cushing's disease 16% (17/108) 3 Metabolic syndrome 72% (78/108) 4 Type 1 diabetes mellitus 6% (6/108) 5 Cirrhosis of the liver 0% (0/108) M 2 Question Complexity D Question Importance Select Answer to see Preferred Response SUBMIT RESPONSE 3 Review Tested Concept Review Full Topic Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK
All Videos (0) Endocrine | Metabolic Syndrome Endocrine - Metabolic Syndrome Listen Now 10:21 min 6/1/2022 16 plays 0.0 (0)