Introduction Causes of ↓ PTH release include accidental surgical excision (thyroidectomy) autoimmune destruction of parathyroid glands DiGeorge syndrome congenital absence of parathyroid glands hypomagnesemia ↓ functional adenylate cyclase leading to ↓ PTH activity Can also be caused by resistance of PTH pseudohypoparathyroidism renal tubules do not respond in presence of PTH aka Albright hereditary osteodystrophy AD inheritance Presentation Symptoms tetany (hypocalcemia) Physical exam Chvostek's sign contraction of facial muscles when tapped rapidly Trousseau's sign carpal spasm following occlusion of brachial artery with BP cuff findings unique to pseudohypoparathyroidism (Albright hereditary osteodystrophy) shortened 4th/5th digits Turners syndrome only involves 5th digit short stature Evaluation Serology hypocalcemia hyperphosphatemia Treatment Medical calcium + calcitriol (D3) supplemenation teriparatide recombinant PTH
QUESTIONS 1 of 5 1 2 3 4 5 Previous Next Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK (M1.EC.14.35) A 1-year-old boy presents to pediatrics clinic for a well-child visit. He has no complaints. He has a cleft palate and an abnormal facial appearance. He has been riddled with recurrent infections and is followed by cardiology for a ventricular septal defect (VSD). Vital signs are stable, and the patient's physical exam is benign. If this patient's medical history is part of a larger syndrome, what might one also discover that is consistent with the manifestations of this syndrome? QID: 105433 Type & Select Correct Answer 1 Kidney stones 6% (7/110) 2 B-cell deficiency 11% (12/110) 3 A positive Chvostek's sign 60% (66/110) 4 A shortened QT Interval 11% (12/110) 5 Hypoactive deep tendon reflexes 10% (11/110) M 2 Question Complexity E Question Importance Select Answer to see Preferred Response SUBMIT RESPONSE 3 Review Tested Concept Review Full Topic
All Videos (0) Endocrine | Hypoparathyroidism Endocrine - Hypoparathyroidism Listen Now 9:15 min 1/18/2022 38 plays 5.0 (1)