Updated: 6/14/2018

Waterhouse-Friderichsen Syndrome

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Introduction
  • Cause of acute adrenocortical insufficiency
  • Typically follows Neisseria meningitidis septicemia  
    • infection causes endotoxic shock and DIC
    • leads to consequent bilateral adrenal hemorrhage and infarction
Presentation
  • Physical exam
    • meningitis with petechial lesions

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