Updated: 6/14/2018

Waterhouse-Friderichsen Syndrome

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  • Introduction
    • Cause of acute adrenocortical insufficiency
    • Typically follows Neisseria meningitidis septicemia
      • infection causes endotoxic shock and DIC
      • leads to consequent bilateral adrenal hemorrhage and infarction
  • Presentation
    • Physical exam
      • meningitis with petechial lesions

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