Overview Airway lining pseudostratified ciliated columnar cells extend to the bronchioles mucus secretions are swept out of the lungs toward the mouth by ciliated cells smoking causes these cells to undergo metaplasia replaced by stratified squamous simple ciliated columnar epithelium extends to the terminal bronchioles ciliated cuboidal cells extend to the respiratory bronchioles alveolar sac are composed of pneumocytes macrophages clear debris in alveoli goblet cells extend to the larger bronchioles but stop before the terminal bronchioles Type I pneumocytes 97% of alveolar surfaces line the alveoli squamous thin for optimal gas diffusion form blood-gas barrier with pulmonary capillary endothelial cells Type II pneumocytes 3% of alveolar surfaces secrete pulmonary surfactant within lamellar bodies dipalmitoyl phosphatidylcholine lowers the alveolar surface tension cuboidal and clustered serve as precursors to type I cells and other type II cells proliferate during lung damage Club (Clara) cells nonciliated columnar with secretory granules secrete component of surfactant degrade toxins act as reserve cells A lecithin-to-sphingomyelin ratio of > 2.0 in amniotic fluid is indicative of fetal lung maturity
QUESTIONS 1 of 7 1 2 3 4 5 6 7 Previous Next Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK (M1.PL.15.71) A 67-year-old male with a 40 pack-year history of smoking visits his physician with a complaint of coughing up blood and recent unintentional weight loss. The physician is concerned about lung cancer given the patient's smoking history. A full workup demonstrates a suspicious lung mass and a lung biopsy is subsequently performed. Which of the following figures correctly demonstrates the type of epithelium which is normally found in the tracheobronchial tree? QID: 106495 FIGURES: A B C D E Type & Select Correct Answer 1 Figure A 5% (6/131) 2 Figure B 6% (8/131) 3 Figure C 2% (2/131) 4 Figure D 5% (7/131) 5 Figure E 79% (104/131) M 1 Question Complexity D Question Importance Select Answer to see Preferred Response SUBMIT RESPONSE 5 Review Tested Concept Review Full Topic (M1.PL.14.70) A 67-year-old man is hospitalized after several days of fever and increasing shortness of breath. Respiratory viral panel returns positive for influenza A and the patient is started on a standard five day course of oseltamivir. Despite therapy, his shortness of breath continues to worsen and his oxygen saturation decreases to the point where ICU transfer and intubation are required. Chest radiograph shows bilateral infiltrates. Clinical criteria are consistent with development of Acute Respiratory Distress Syndrome (ARDS). After several weeks of supportive therapy, the patient improves with lung function returning to near normal. Which of the following processes is involved in the regeneration of alveolar lining after damage to alveoli occurs? QID: 106485 Type & Select Correct Answer 1 Squamous cell proliferation 4% (4/100) 2 Sweeping of debris out of the alveoli by ciliated cells 1% (1/100) 3 Excess mucus production by goblet cells 1% (1/100) 4 Proliferation of surfactant-secreting cells 84% (84/100) 5 Proliferation of club cells 7% (7/100) M 1 Question Complexity E Question Importance Select Answer to see Preferred Response SUBMIT RESPONSE 4 Review Tested Concept Review Full Topic
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