Snapshot A 76-year-old man is brought to the clinic by his son, who has been concerned about his father's mental decline in the past few years. He says that his father moved in with him 3 years ago because he was having trouble paying his bills and maintaining his house alone. In the past year, his father has begun to have trouble dressing himself without assistance and has had multiple episodes of wandering around the neighborhood and being unable to find his way back to his son's home. Upon questioning, the patient is able to state his first and last name and is aware that he is in the hospital but struggles to remember the date. When asked to remember 3 simple items, he is unable to recall all but 1 of them after 5 minutes. He is pleasant and alert but remains mostly quiet and repeats himself when asked more detailed questions about his day. Introduction Overview login to view 1 more bullet Epidemiology login to view 5 more bullets Pathophysiology login to view 16 more bullets Prognosis login to view 4 more bullets Presentation Symptoms login to view 9 more bullets Physical exam login to view 14 more bullets Imaging Noncontrast head CT or MRI login to view 1 more bullet Studies Laboratory studies login to view 2 more bullets Differential Normal aging login to view 2 more bullets Major depressive disorder login to view 3 more bullets Treatment Lifestyle login to view 3 more bullets Medical login to view 4 more bullets