Psychiatric Drug Introduction Psychiatric medications can be broken down into the following categores antidepressants antipsychotics bipolar medications anxiolytics Overview Drugs non-selective inhibitors phenelzine tranylcypromine isocarboxazid MAO-B selective inhibitor selegiline login to view 1 more bullet Mechanism ↓ MAO → ↓ amine degradation → ↑ levels of amine neurotransmitters (mainly NE, 5-HT) Clinical use atypical depression anxiety hypochondriasis Toxicity hypertensive crisis caused by tyramine ingestion login to view 2 more bullets other sympathomimetics CNS stimulation contraindicated with other 5-HT altering drugs (SSRIs, SNRIs) or meperidine to prevent serotonin syndrome