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Updated: Oct 12 2020

Drug Reactions and Side Effects

  • Overview
    • Drug reactions organized by system
      • cardiovascular
      • GI
      • musculoskeletal
      • neurologic
      • renal
      • reproductive/endocrine
      • respiratory
      • multiorgan
    • Type A reactions
      • predictable
      • common
      • mild and self resolving
      • dose-dependent
    • Type B reactions
      • unpredictable
      • rare
      • severe
      • idiosyncratic
      • not dose-dependent
  • Medication Reactions
      • Cardiovascular
      • Reaction
      • Causal Agent
      • Atropine-like side effects
      • TCAs
      • Coronary vasospasm
      • Cocaine
      • Sumatriptan
      • Cutaneous flushing
      • Vancomycin
      • Adenosine
      • Niacin (reduced by co-administration of aspirin)
      • Calcium channel blockers
      • Dilated cardiomyopathy
      • Doxorubicin (Adriamycin)
      • Daunorubicin
      • Trastuzumab
      • Cocaine
      • Torsades de pointes
      • Class IA antiarrhythmic (disopyramide, quinidine, procainamide)
      • Class III antiarrhythmics (amiodarone, sotalol)
      • Lithium
      • Chloroquine
      • Erythromycin, clarithromycin
      • Haloperidol, thioridazine, ziprasidone
      • GI
      • Reaction
      • Causal Agent
      • Acute cholestatic hepatitis
      • Macrolides
      • Troglitazone
      • Focal to massive hepatic necrosis
      • Halothane
      • Valproic acid
      • Acetaminophen
      • Amanita phalloides
      • Carbon tetrachloride
      • Hepatitis
      • INH
      • Phenytoin
      • Methyldopa
      • Pseudomembranous colitis
      • Clindamycin
      • Ampicillin
      • Hematologic
      • Reaction
      • Causal Agent
      • Agranulocytosis
      • Clozapine
      • Carbamazepine
      • Colchicine
      • Propylthiouracil
      • Methimazole
      • Dapsone
      • Cephalosporins
      • Aplastic anemia
      • Chloramphenicol
      • Benzene
      • NSAIDs
      • Propylthiouracil
      • Methimazole
      • Carbamazepine
      • Phenytoin
      • Direct Coombs-positive hemolytic anemia
      • Methyldopa
      • Penicillin
      • Gray baby syndrome
      • Chloramphenicol
      • Hemolysis in G6PD-deficient patients
      • Isoniazid (INH)
      • Dapsone
      • Sulfonamides
      • Primaquine
      • Chloroquine
      • Aspirin
      • Ibuprofen
      • Nitrofurantoin
      • Methylene blue
      • Megaloblastic anemia
      • Phenytoin
      • Methotrexate
      • Sulfonamides
      • 6-mercaptopurine
      • Cytosine arabinoside
      • Thrombotic complications
      • Contraceptives
      • Musculoskeletal
      • Reaction
      • Causal Agent
      • Gingival hyperplasia
      • Phenytoin
      • Cyclosporin
      • Nifedipine
      • Gout
      • Furosemide
      • Thiazides
      • Cyclosporin
      • Levodopa
      • Niacin
      • Osteoporosis
      • Corticosteroids
      • Heparin
      • Proton pump inhibitors
      • Lithium
      • Photosensitivity
      • Sulfonamides
      • Amiodarone
      • Tetracycline
      • Fluoroquinolones
      • Rash (Stevens-Johnson syndrome)
      • Ethosuximide
      • Lamotrigine
      • Carbamazepine
      • Phenobarbital
      • Phenytoin
      • Sulfonamides
      • Fluorquinolones
      • Furosemide
      • Penicillin
      • Allopurinol
      • Rhabdomyolysis
      • Statins
      • SLE-like syndrome
      • Hydralazine
      • INH
      • Procainamide
      • Phenytoin
      • Carbamazepine
      • Tendonitis, tendon rupture, and cartilage damage in children
      • Fluoroquinolones
      • Neurologic
      • Reaction
      • Causal Agent
      • Cinchonism
      • Quinidine
      • Quinine
      • Diabetes insipidus
      • Lithium
      • Demeclocycline
      • Parkinson-like syndrome
      • Haloperidol
      • Chlorpromazine
      • Reserpine
      • Metoclopramide
      • MPTP (causes permanent Parkinson's)
      • Clozapine
      • Prochlorperazine
      • Cinnarizine
      • Seizures
      • Bupropion
      • Venlafazine
      • Tramadol
      • Diphenhydramine
      • Imipenem/cilastatin
      • Isoniazid
      • Tardive dyskinesia
      • Antipsychotics (chlorpromazine)
      • Renal/GU
      • Reaction
      • Causal Agent
      • Fanconi's syndrome
      • Expired tetracycline
      • Tenofovir
      • Interstitial nephritis
      • Methicillin
      • NSAIDs
      • Acetominophen
      • Furosemide
      • Allopurinol
      • Hemorrhagic cystitis
      • Cyclophosphamide
      • Ifosfamide (prevented by mesna administration)
      • Reproductive/Endocrine
      • Reaction
      • Causal Agent
      • Adrenocortical insufficiency
      • Withdrawal of glucocorticoid therapy
      • Gynecomastia
      • SpironolactoneDigitalisCimetidineClomipheneBusulfan, nitrourea, vincristine (direct testicular injury)
      • Hot Flashes
      • Tamoxifen
      • Clomiphene
      • Hypothyroidism
      • Lithium
      • Amiodarone
      • Neck radiation therapy
      • Respiratory
      • Reaction
      • Causal Agent
      • Cough
      • ACE inhibitors
      • Pulmonary fibrosis
      • Bleomycin
      • Amiodarone
      • Busulfan
      • Methotrexate
      • Cyclophosphamide
      • Hydralazine
      • Tocainide
      • Multiorgan
      • Reaction
      • Causal Agent
      • Disulfiram-like reaction
      • Sulfonylurea
      • Metronidazole
      • Nephrotoxicity/neurotoxicity
      • Polymyxins
      • Nephrotoxicity/ototoxicity
      • Aminoglycosides (neomycin)
      • Vancomycin
      • Loop diuretics (ethacrynate, furosemide, bumetanide)
      • Cisplatin
      • Mercuric chloride
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