Please confirm topic selection

Are you sure you want to trigger topic in your Anconeus AI algorithm?

Updated: 4/28/2022

Alpha-Blockers

0%
Topic
Review Topic
0
0
N/A
N/A
Questions
3
0
0
Topic
Images
https://upload.medbullets.com/topic/107019/images/alphablockers1.jpg
https://upload.medbullets.com/topic/107019/images/jhzhij0uceouwfp6-d9reg.jpg
  • α-Blockers
      • Nonselective Î±-Blockers
      • Clinical Applications
      • Toxicity
      • Phenoxybenzamine (irreversible, preferred)
      • Pheochromocytoma
      • High catecholamine states
      • Orthostatic hypotension
      • Reflex tachycardia
      • Phentolamine (reversible)
      • Pheochromocytoma
      • High catecholamine states
      • Orthostatic hypotension
      • Reflex tachycardia
      • Selective α1-blockers (-zosin)
      • Drug
      • Clinical Applications
      • Toxicity
      • Prazosin
      • Hypertension
      • Urinary retention in benign prostatic hyperplasia (tamulosin is the most specific for urinary symptoms)
      • First dose orthostatic hypotension
      • Headache and dizziness
      • Doxazosin
      • Hypertension
      • Urinary retention in benign prostatic hyperplasia (tamulosin is the most specific for urinary symptoms)
      • First dose orthostatic hypotension
      • Headache and dizziness
      • Terazosin
      • Hypertension
      • Urinary retention in benign prostatic hyperplasia (tamulosin is the most specific for urinary symptoms)
      • First dose orthostatic hypotension
      • Headache and dizziness
      • Tamulosin
      • Hypertension
      • Urinary retention in benign prostatic hyperplasia (tamulosin is the most specific for urinary symptoms)
      • First dose orthostatic hypotension 
      • Headache and dizziness
      • Selective α2 blockers
      • Drug
      • Clinical Applications
      • Toxicity
      • Mirtazapine
      • Depression
      • Sedation
      • Xerostomia
      • ↑ serum cholesterol
      • ↑ appetite
      • Yohimbine
      • Male erectile dysfunction
      • Hypotension
      • Anxiety
  • α-Blockers + Sympathomimetics effects
    • Epi + α-blocker
      • before non selective α-blocker is given, epi's net effect is to increase heart rate, contractility, and vasoconstriction leading a net pressor effect on blood pressure
      • after α-blocker is given, epi's α response is blocked while its β2 response remains leading to net depressor effect on blood pressure (top of image)
        • β2 is Gs coupled, increases cAMP, causes vasodilation
        • α is Gq coupled, increases calcium causes vasoconstriction
    • Epi + β-blocker
      • before nonselective α-blocker is given, epi's net effect is to increase heart rate, contractility, and vasoconstriction leading a net pressor effect on blood pressure
      • after β-blocker given, epi's β response is blocked, while α response remains leading to net pressor effect (bottom of image)
    • Phenylephrine + α-blocker
      • phenylephrine (α1 > α2 agonist) leads to a net pressor effect on blood pressure
      • administration of a nonselective α-blocker leads a net zero effect on blood pressure

Please rate this review topic.

You have never rated this topic.

Thank you. You can rate this topic again in 12 months.

Flashcards (0)
Cards
1 of 0
Questions (3)
Question locked
Sorry, this question is for
PEAK Premium Subscribers only
Upgrade to PEAK
Question locked
Sorry, this question is for
PEAK Premium Subscribers only
Upgrade to PEAK
Question locked
Sorry, this question is for
PEAK Premium Subscribers only
Upgrade to PEAK
VIDEOS & PODCASTS (1)
EXPERT COMMENTS (12)
Private Note