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Overview
  • Efficacy 
    • maximum effect that a drug can produce regardless of dose
  • Potency 
    • amount of a drug that is needed to produce a given effect 
      • e.g., EC50 is the concentration or dose of drug that causes 50% of maximum effect
    • determined by affinity of drug for receptor and number of receptors available
 

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(M1.PH.75) A laboratory is conducting a study to assess the safety, efficacy, and potency of a group of drugs before allowing the agents to proceed to clinical trials. Figure A shows the dose-response curves for four different drugs from the same class of medications (Drugs A, B, C, & D). Which of the following is true regarding these medications? Review Topic

QID: 106864
FIGURES:
1

Drug A has greater efficacy than Drug D

10%

(2/21)

2

Drug D has greater efficacy than Drug A

0%

(0/21)

3

Drug A has greater potency than Drug D

81%

(17/21)

4

Drug D has greater potency than Drug A

0%

(0/21)

5

All four drugs (A,B,C,D) have equal potencies

5%

(1/21)

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