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Updated: Aug 6 2019

Euthyroid Sick Syndrome (ESS)

5.0

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https://upload.medbullets.com/topic/109065/images/116364-138560-118651-118787.jpg
  • Introduction
    • Apparent alterations to thyroid hormone level with normal thyroid gland function
      • peripheral activity of outer ring deiodinase is ↓
        • normally converts T4 to T3
      • peripheral activity of inner ring deiodinase is ↑
        • normally converts T4 to reverse T3
    • Likely a response to an acute/chronic illness
      • cancer
      • cardiac disease (MI, CHF)
      • CRF
      • sepsis
  • Evaluation
    • Serology
      • ↓ total serum T4/T3
      • normal serum TSH
      • ↑ reverse T3
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