Growth Hormone Adenoma / Acromegaly

(M1.EC.17.4720) A 65-year-old woman presents to her primary care doctor with progressively worsening headaches over the last few years. She has recently been diagnosed with diabetes mellitus and started metformin a week ago. She has no other significant past medical history and has never smoked. Her husband also reports that her face has changed over the past few months. An earlier photograph of this patient and her current appearance are shown side by side in Figure A. Which of the following would most likely be the best test for diagnosing this patient?

(M1.EC.15.75) A 38-year-old man presents to the endocrinologist with complaints of increased shoe size and headaches in the morning. These symptoms have developed gradually over the past year but have become especially concerning because he can no longer wear his normal-sized boots. He denies any other symptoms, including visual changes. He was recently started on lisinopril by his primary care physician for high blood pressure. His vital signs are within normal limits and stable. On exam, the endocrinologist notes the findings shown in Figures A and B. These facial features are especially striking when contrasted with his drivers license from 10 years prior, when his jaw was much less prominent. The endocrinologist sends a screening blood test to work-up the likely diagnosis. Which of the following organs or glands produces the molecule being tested in this screening?