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Updated: Nov 11 2015

Muscarinic Antagonists

Pirenzepine
  • Also propantheline
  • Clinical use
    • peptic ulcer
      • PPI use is prefered due to less side effects
  • Toxicity
    • general antimuscarinic side effects
      • tachycardia
      • xerostomia
      • difficulty focusing eyes
Scopolamine
  • Mechanism
    • blocks M1 receptors in the vomitting center
  • Clinical use
    • motion sickness
  • Toxicity
    • sedation
    • short-term memory block
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