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A 22-year-old G2P1 female presents to the clinic at the beginning of her third trimester for a fetal ultrasound. The sonographer is unable to visualize any of the structures arising from the mesonephric duct. This infant is at risk for malformation of which of the following?
Upper 1/3 of vagina
Lower 2/3 of vagina
No malformation would be expected
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A 35-year-old female presents to her gynecologist complaining of vaginal discomfort. She reports that over the past two weeks, she has developed dyspareunia and feels as if there is a mass on the external aspect of her vagina. She is sexually active in a monogamous relationship. On physical examination, there is a 2 cm unilateral erythematous swelling on the right side of the posterolateral labia minora. Which of the following embryologic precursors gives rise to the affected tissue in this patient?
A 4-day-old healthy male infant is born with normal internal and external male reproductive organs. Karyotype analysis reveals a 46XY genotype. Production of what substance by which cell type is responsible for the development of the normal male seminal vesicles, epididymides, ejaculatory ducts, and ductus deferens?
Testis-determining factor; Sertoli cells
Testis-determining factor; Leydig cells
Testosterone; Sertoli cells
Testosterone; Leydig cells
Mullerian inhibitory factor; Sertoli cells
A newborn infant with karyotype 46, XY has male internal and external reproductive structures. The lack of a uterus in this infant can be attributed to the actions of which of the following cell types?