Snapshot A 60-year-old man presents to the emergency room with a 1-day history of fever and a new skin rash. He is taking methicillin for a soft tissue infection. On physical exam, he has costovetebral tenderness, and a diffuse maculopapular rash over his trunk. His serum creatinine is elevated at 3 mg/dL. Urinalysis reveals white blood cells. Further testing with Wright stain is positive for eosinophils in the urine. Introduction Clinical definition login to view 1 more bullet Epidemiology login to view 2 more bullets Etiology login to view 12 more bullets Pathogenesis login to view 2 more bullets Prognosis login to view 1 more bullet Presentation Symptoms login to view 5 more bullets Physical exam login to view 3 more bullets Studies Labs login to view 2 more bullets Urinalysis with microscopy and sediment analysis login to view 4 more bullets Renal biopsy login to view 1 more bullet Histology login to view 3 more bullets Diagnostic criteria login to view 2 more bullets Differential Acute tubular necrosis from NSAIDs login to view 1 more bullet Renal atheroemboli login to view 2 more bullets Treatment Conservative login to view 3 more bullets Medical login to view 3 more bullets Complications Renal failure requiring dialysis