Snapshot A 46-year-old woman is admitted to the ICU with severe pancreatitis. During the first 24 hours of admission, severe hypoxemia that requires ventilatory support with high concentrations of inspired oxygen develop. On exam the patient has rhonchi and crackles bilaterally. An arterial blood gas collected at 60% FiO2 reveals pH 7.42, PCO2 35 mmHg, and PO2 108 mmHg. Introduction Defined asacute diffuse, inflammatory lung injury leading to increased vascular permeability, increased lung weight and loss of aerated lung tissue login to view 4 more bullets Causes login to view 9 more bullets Presentation Symptoms login to view 1 more bullet Physical exam login to view 2 more bullets Evaluation ards Arterial blood gas login to view 3 more bullets Radiology login to view 2 more bullets Histology login to view 2 more bullets Severity graded on PaO2 / FiO2 ratio and required PEEP (see below) Treatment Respiratory support & treat underlying cause login to view 7 more bullets