Overview Snapshot A 32-year-old previously healthy man develops headache, fatigue, vomiting, and shortness of breath about 12 hours after arriving to Mt. Everest Base Camp. Over the next day, he develops mild difficulty walking, and confusion. He is seen by a physician who administers a medication and advises him to rest. His symptoms improve over the next 24-48 hours. (Acetazolamide) Mannitol Mechanism login to view 3 more bullets Clinical use login to view 8 more bullets Toxicity login to view 3 more bullets Contraindications login to view 2 more bullets Acetazolamide Mechanism login to view 7 more bullets loss of bicarbonate results in metabolic acidosis Clinical use login to view 6 more bullets Toxicity login to view 8 more bullets