Snapshot A 54-year-old man presents to his primary care physician with chest pain. His chest pain began approximately 2 weeks ago and worsens when taking deep breaths. He reports that sitting up and leaning forward improves his symptoms and that his chest pain is not associated with exertion. He says that his symptoms are associated with mild shortness of breath and fatigue. Medical history is significant for type 2 diabetes mellitus, hyperlipidemia, and hypertension. He has been non-adherent to his medications. Social history is notable for smoking 1 pack of cigarettes per day for 20 years. Vital signs are significant for a blood pressure of 163/112 mmHg. On physical examination, there is a pericardial friction rub and peripheral edema. On laboratory testing, his glomerular filtration rate (GFR) 48 mL/minute/1.73 m2. Introduction Clinical definition login to view 3 more bullets Epidemiology login to view 10 more bullets Etiology login to view 2 more bullets Pathogenesis login to view 16 more bullets Prognosis login to view 1 more bullet Presentation Symptoms login to view 8 more bullets Physical exam login to view 7 more bullets Imaging Renal ultrasound login to view 4 more bullets Studies Labs login to view 14 more bullets Biopsy login to view 1 more bullet Differential Acute on chronic kidney disease Treatment Conservative login to view 3 more bullets Medical login to view 22 more bullets Operative login to view 3 more bullets Complications Anemia Mineral and bone disease Hypertension Hypervolemia Depression Cardiovascular disease