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Updated: 11/27/2020

Recombinant Cytokines

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  • Snapshot
    • A 56-year-old man presents to his primary care physician due to shortness of breath and fatigue. He reports that these symptoms have progressively worsened over the course of a few weeks. Medical history is significant for type II diabetes mellitus and chronic kidney disease with his last eGFR reading at 82 mL/min/1.73 m2. He has yet to need dialysis. Laboratory testing is significant for a hemaglobin of 9.5 g/dL and an eGFR of 55 mL/min/1.73 m2. After further evaluation of non-renal causes of anemia it was determined that erythropoietin should be added to his treatment regimen to improve his symptoms.
  • Introduction
      • Immunosuppressants
      • Medication
      • Mechanism of Action
      • Clinical Use
      • Aldesleukin
      • IL-2 product which leads to
        • T-, B-cell, and NK cells
          • proliferation
          • differentiation
          • recruitment
      • Metastatic renal cell carcinoma
      • Metastatic melanoma
      • Erythropoietin (epoetin alfa)
      • Stimulates erythroid progenitor cells to
        • divide and differentiate
      • Anemia
      • Sargramostim
      • Granulocyte colony stimulating factors to result in neutrophil
        • proliferation
        • differentiation
        • activation
      • To recover
        • white count and bone marrow
      • IFN-α
      • Multiple effects
      • Chronic hepatitis B and C
      • Malignant melanoma
      • Condyloma acuminatum
      • Hairy cell leukemia
      • Kaposi sarcoma
      • IFN-β
      • Multiple effects
      • Multiple sclerosis
      • IFN-γ
      • Multiple effects
      • Chronic granulomatous disease
      • Romiplostim (thrombopoietin)
      • A thrombopoietin (TPO) analog that acts on the TPO receptor to
        • ↑ platelet count
      • Thrombocytopenia
      • Eltrombopag
      • A TPO agonist that leads to
        • ↑ platelet count
      • Thrombocytopenia
      • Oprelvekin (IL-11)
      • A thrombopoietic growth factor that results in
        • ↑ platelet count
      • Thrombocytopenia
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