Snapshot atopic dermatitis A 7-year-old patient presents to the emergency room after a motor vehicle accident, in which she loses a lot of blood. She is immediately transfused with blood. However, she develops difficulty breathing and oral-facial swelling. Physical exam reveals expiratory wheezes. She is immediately given epinephrine. On further questioning, physical exam reveals atopic dermatitis and recurrent ear and lung infections. Introduction Primary immunodeficiency with decreased levels of IgA Epidemiology login to view 1 more bullet Pathogenesis login to view 3 more bullets Associated conditions login to view 6 more bullets Presentation Symptoms login to view 4 more bullets Evaluation Diagnosis based on clinical history Serology login to view 3 more bullets Differential Common variable immunodeficiency IgG deficiency Ataxia-telangiectasia (↓ IgA, IgG, and IgE) Hyper-IgM syndrome (↓ IgA, IgG, IgE, and ↑ IgM) Treatment Usually no specific treatment Antibiotics as needed for infections Immunizations Blood transfusions login to view 1 more bullet Prognosis, Prevention, and Complications Prognosis login to view 2 more bullets Prevention login to view 1 more bullet Complications login to view 3 more bullets