Snapshot A 75-year-old woman living in a nursing home presents with a 1-month history of severe pruritus. She reports having unrelenting pruritis with a pink rash over her trunk and extremities. Though she tried multiple lotions, the pruritus does not improve. Approximately 2 days ago, she also noticed some blisters on her body. She has never had rashes like this before. On physical exam, she has several 1-3 cm tense bullae on her abdomen and upper arms. Nikolsky sign is negative. A skin biopsy is taken and sent for immunofluorescence. Introduction Bullous pemphigoid Clinical definition login to view 1 more bullet Epidemiology login to view 2 more bullets Pathogenesis login to view 4 more bullets Associated conditions login to view 8 more bullets Prognosis login to view 2 more bullets Presentation Symptoms login to view 2 more bullets Physical exam login to view 7 more bullets Studies Labs login to view 4 more bullets Histology login to view 3 more bullets Differential Pemphigus vulgaris login to view 3 more bullets Treatment Conservative login to view 7 more bullets Medical login to view 14 more bullets Complications Skin and soft tissue bacterial infection of open lesions