Snapshot A 3-year-old girl presents to her pediatrician with a widespread rash. She recently had fevers and a sore throat. She has perioral fissues and a desquamating rash in the groin and neck. When light pressure is applied, the skin easily sloughs off. Superficial wound cultures and bacterial cultures are negative. Introduction Staphylococcal scalded skin syndrome. Clinical definition login to view 1 more bullet Epidemiology login to view 4 more bullets Pathophysiology login to view 4 more bullets Associated Staphylococcus aureus conditions login to view 4 more bullets Prognosis login to view 2 more bullets Presentation Symptoms login to view 2 more bullets Physical exam login to view 8 more bullets Studies Labs login to view 2 more bullets Biopsy login to view 2 more bullets Histology login to view 1 more bullet Differential Toxic epidermal necrolysis login to view 1 more bullet Bullous impetigo login to view 3 more bullets Treatment Medical login to view 6 more bullets Complications Secondary infection of denuded skin