Snapshot A 42-year-old man presents to his dermatologist for management of his psoriasis. He reports an itchy and rough rash along his elbows, knees, and scalp. While he was previously treated for this disease in childhood, he has been off treatment for years. Physical exam reveals 2-7 cm pink plaques with overlying silvery scales. When the scale is scratched off, there is pinpoint bleeding. He is started on an intensive topical therapy regimen with corticosteroids and vitamin D analog. Introduction Clinical definition login to view 2 more bullets Epidemiology login to view 11 more bullets Etiology login to view 2 more bullets Pathogenesis login to view 2 more bullets Associated conditions login to view 1 more bullet Presentation Fingernails seen in psoriasis Symptoms login to view 3 more bullets Physical exam login to view 10 more bullets Studies Labs login to view 2 more bullets Histology login to view 4 more bullets Differential Atopic dermatitis Seborrheic dermatitis Treatment Conservative login to view 3 more bullets Medical login to view 30 more bullets Complications Psoriatic arthritis Other HLA-B27 associated autoimmune diseases