Snapshot A 25-year-old man presents to the emergency department for a nosebleed. He says that the bleeding began earlier in the morning and occurred spontaneously. He denies any trauma to the nose or inhaling medications or illicit drugs through the nose. He has tried applying pressure to the nose but the bleeding still persists. He has a history of multiple episodes of epistaxis requiring medical attention. On physical exam, he has multiple telangiectasias on his lips. Introduction Definition login to view 5 more bullets Pathophysiology login to view 1 more bullet Presentation Clinical presentation login to view 10 more bullets Studies Iron deficiency anemia login to view 1 more bullet Treatment Management is directed at the site of involvement login to view 1 more bullet Complications Hemorrhagic and embolic stroke Iron deficiency anemia Gastrointestinal bleeding Pulmonary hypertension