Snapshot A 35-year-old man with a history of alcoholism is brought to the emergency room after being found clutching his abdomen at a grocery store. He is currently intoxicated. He reports significant pain in his epigastrium. A complete blood count shows anemia and thrombocytopenia. Lipase and amylase levels are both elevated. A peripheral blood smear shows schistocytes. Additional lab testing reveals elevated D-dimer and low fibronigen levels. (Pancreatitis-induced disseminated intravascular coagulation) Introduction Overview login to view 1 more bullet Epidemiology login to view 11 more bullets Pathogenesis login to view 6 more bullets Presentation Physical exam login to view 9 more bullets Studies Diagnosis is based on clinical and laboratory findings, including thrombocytopenia, coagulation factor consumption, and fibrinolysis Serum labs login to view 8 more bullets Peripheral blood smear with microangiopathic changes login to view 1 more bullet Differential Heparin-induced thrombocytopenia login to view 2 more bullets Treatment Medical login to view 10 more bullets Complications Renal failure Liver injury Neurologic symptoms login to view 1 more bullet Waterhouse-Friderichsen syndrome login to view 2 more bullets Purpura fulminans login to view 2 more bullets