Updated: 11/30/2016

Prothrombin Gene Mutation

Review Topic
  • A mutation in the prothrombin gene that results in increased expression
    • a point mutation is in the 3' untranslated region (20210A)
  • Resultant state of hypercoagulability via increase in thrombin
  • Symptoms
    • recurrent DVTs
    • DVTs beginning at a young age
Prognosis, Prevention, and Complications
  • Female patients should not use oral contraception, which can increase the hypercoagulable state by increasing coagulation factor synthesis

Please rate topic.

Average 5.0 of 1 Ratings

Thank you for rating! Please vote below and help us build the most advanced adaptive learning platform in medicine

The complexity of this topic is appropriate for?
How important is this topic for board examinations?
How important is this topic for clinical practice?
Topic COMMENTS (6)
Private Note