Updated: 4/24/2019

Microangiopathic Anemia

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Introduction

  • RBCs are damaged in systemic circulation due to sharp microthrombi lining small vessels
  • Associated conditions
    • DIC
    • TTP-HUS
    • SLE
    • malignant hypertension
Presentation
  • Symptoms
    • anemia
Evaluation
  • Blood smear 
    • schistocytes (helmet cells) (indicated by arrow in image above)
      • due to shearing mechanical destruction
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