Snapshot A 25-year-old woman presents to her primary care physician’s office for her annual physical. She recently immigrated from a developing country and reports having multiple episodes of pharyngitis in the past. On physical exam, there is a holosystolic murmur at the apex. A follow-up echocardiogram shows mitral regurgitation, concerning for rheumatic heart disease. Introduction Clinical definition login to view 1 more bullet Epidemiology login to view 11 more bullets Etiology login to view 1 more bullet Pathogenesis login to view 11 more bullets Associated conditions login to view 6 more bullets Prognosis login to view 2 more bullets Presentation Symptoms login to view 3 more bullets Physical exam login to view 12 more bullets Imaging Echocardiography login to view 5 more bullets Studies Labs login to view 1 more bullet Histology login to view 1 more bullet Making the diagnosis login to view 1 more bullet Differential Infective endocarditis login to view 4 more bullets Treatment Management approach login to view 5 more bullets Medical login to view 7 more bullets Operative login to view 6 more bullets Complications Aortic regurgitation Cardiac arrhythmias Heart failure