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Review Question - QID 214933

Targeted Therapy Rituximab Mechanism QID: 214933 (M1.OMB.4754)
In scope icon M 3 A
QID 214933 (Type "214933" in App Search)
A 73-year-old woman presents to primary care for her annual wellness visit. She has noticed some generalized fatigue and weight loss over the past 2 months but attributes it to a slow recovery from the flu. She denies feeling down or depressed and continues to have interest in her daily activities. The patient reports no other medication use other than her daily hydrochlorothiazide for chronic hypertension. Her temperature is 98.2°F (36.8°C), blood pressure is 124/72 mmHg, pulse is 68/min, and respirations are 12/min. Physical exam is notable for symmetrically enlarged, painless cervical lymph nodes bilaterally. Initial lab work is as follows:

Hemoglobin: 11.0 g/dL
Hematocrit: 42%
Leukocyte count: 28,000/mm^3
Platelet count: 350,000/mm^3

A peripheral blood smear is shown in Figure A. Which of the following drugs would most likely target the cell-type demonstrated by the arrow in Figure A?
  • A
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  • A