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Review Question - QID 214755

Chromatin Structure Overview Euchromatin/heterochromatin QID: 214755 (M1.OMB.1)
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QID 214755 (Type "214755" in App Search)
A scientist is studying a novel skin disease that is inherited in an X-linked dominant manner. She finds that the disease is variably expressed in different skin regions within the same patient and takes samples from multiple different locations to identify the source of the discrepancy. She isolates the nucleus of cells from different regions and uses a labeled oligomeric ribonucleic acid to determine the location of the mutant gene. She finds that normal patches of skin have the mutant gene localized to the periphery of the nucleus in dense, closely packed regions of chromatin. Which of the following mechanisms is most directly decreased by this method of organization?
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