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Review Question - QID 214697

Sickle Cell Anemia Introduction Pathogenesis QID: 214697 (M1.OMB.4698)
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QID 214697 (Type "214697" in App Search)
A 10-year-old boy is brought to his pediatrician due to complaints of pain in his hands and feet during swimming practice. While the patient’s parents have not had comparable symptoms in the past, the pediatrician learns that the patient’s maternal grandmother also had similar pain events in her youth. On physical examination, the pediatrician notices that the patient has an enlarged upper jaw and prominent frontal bossing. His blood smear is shown in Figure A. What is the pathophysiology for this patient’s condition?
  • A
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  • A