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Review Question - QID 214610

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QID 214610 (Type "214610" in App Search)
A 1-day-old infant boy is brought to the emergency department by his parents after their midwife advised them to seek care immediately after birth. The parents have no past medical history and did not seek pre-natal care. On presentation, he is found to have small eyes, a cleft palate, a small head, and extra digits on both fingers. Imaging reveals cystic kidneys and no longitudinal separation between cerebral hemispheres. An abnormality in which of the following chromosomes is most likely responsible for this patient's disorder?