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Review Question - QID 214381

Aplastic Anemia Introduction Multiple different causes QID: 214381 (M1.ST.12.76)
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QID 214381 (Type "214381" in App Search)
A 4-year-old-boy presents to the pediatrician's office for increased bruising, petechiae, and fatigue over the past 5 months. Although the patient eats a well-balanced diet and has received all age-appropriate vaccinations, he is at the 4th percentile for height and 12th percentile for weight for his age. When the pediatrician speaks to him, he answers in 2-word phrases. On physical exam, he is noted to have a short stature, multiple flat, brown patches with irregular edges on his back, and hypoplastic thumbs. Laboratory results demonstrate the following:

Hemoglobin: 8.2 g/dL
Mean corpuscular volume: 108/µm³
Platelets: 42,000/mm³
Leukocytes: 3,500/mm³

What biological mechanism explains the cause of his symptoms?
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