Review Question - QID 213868

A geneticist reviews the results of a whole exome sequencing from a patient and notices several de novo mutations in a gene that is involved in the complement cascade. These mutations affect the ability of the protein produced to polymerize into a circular structure; however, they do not appear to compromise the ability of the protein to detect abnormal structures. Furthermore, foreign organisms that are placed into an assay with the mutated protein appear to be opsonized properly but then do not lyse as expected. A patient with the mutations described here will most likely have which of the following clinical manifestations?