Review Question - QID 213847

A 42-year-old woman presents to the physician with a complaint of fatigue and weakness. She states that her muscles often feel sore after a day of light activity, whereas she previously had lived a very active lifestyle. Prior to this month of feeling more lethargic than usual, she had been experiencing night sweats, palpitations, restlessness, and tremors. On physical examination, the patient has a puffy face and findings seen in Figure A. The physician palpates a smooth lump in her anterior neck when the patient swallows. Which of the following autoantibodies is most strongly associated with this patient’s current symptoms?