Review Question - QID 213713

A 21-year-old man presents to this primary care physician because he has noticed an expanding mass in his left thigh. He says that he started noticing a painful nodule in the muscle about 3 months ago, but thought that it was due to pulling a muscle while exercising. Since then he says that it had expanded over time and scheduled his visit after his parents noticed the mass when he came home from college. His mother was diagnosed with invasive ductal carcinoma of the breast when she was 41 years old, and his cousin had childhood leukemia. Biopsy of the lesion shows a high grade malignancy of skeletal muscle cells. Which of the following changes would most likely be seen in this patient?